Inhibitor of Sarco/Endoplasmic Reticulum Calcium-ATPase Impairs Multiple Steps of Paramyxovirus Replication

Sarco/endoplasmic reticulum calcium-ATPase (SERCA) is a membrane-bound cytosolic enzyme which is known to regulate the uptake of calcium into the sarco/endoplasmic reticulum. Herein, we demonstrate for the first time that SERCA can also regulate virus replication. Treatment of Vero cells with SERCA-...

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Main Authors: Naveen Kumar, Nitin Khandelwal, Ram Kumar, Yogesh Chander, Krishan Dutt Rawat, Kundan Kumar Chaubey, Shalini Sharma, Shoor Vir Singh, Thachamvally Riyesh, Bhupendra N. Tripathi, Sanjay Barua
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
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Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00209/full