The Effect of BCR-ABL Specific Tyrosine Kinase Inhibitors on the Thioredoxin System in Chronic Myeloid Leukemia

Chronic myeloid leukemia (CML) is a myeloproliferative disorder that is caused by the formation of a fusion onco-protein, BCR-ABL. Since BCR-ABL plays a role in the progression of CML, the most common treatments of CML are tyrosine kinase inhibitors (TKIs) that specifically target BCR-ABL. However,...

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Bibliographic Details
Main Authors: Erin Clapper, Giovanna Di Trapani, Kathryn F. Tonissen
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Hemato
Subjects:
Online Access:https://www.mdpi.com/2673-6357/2/2/14