Genetic and non‐genetic drug resistance: Darwin or Lamarck?

Drug resistance represents a major limitation to the long‐term efficacy of anti‐cancer treatments. The commonly accepted view is that the selection of inheritable genetic mechanisms governs the development of secondary resistance. However, compelling evidence suggests an important role for adaptive...

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Bibliographic Details
Main Author: Mariangela Russo
Format: Article
Language:English
Published: Wiley 2024-02-01
Series:Molecular Oncology
Subjects:
Online Access:https://doi.org/10.1002/1878-0261.13601