Genetic and non‐genetic drug resistance: Darwin or Lamarck?
Drug resistance represents a major limitation to the long‐term efficacy of anti‐cancer treatments. The commonly accepted view is that the selection of inheritable genetic mechanisms governs the development of secondary resistance. However, compelling evidence suggests an important role for adaptive...
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Format: | Article |
Language: | English |
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Wiley
2024-02-01
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Series: | Molecular Oncology |
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Online Access: | https://doi.org/10.1002/1878-0261.13601 |