Tailoring the stress response of human skin cells by substantially limiting the nuclear localization of angiogenin

Human angiogenin (hANG) is the most studied stress-induced ribonuclease (RNase). In physiological conditions it performs its main functions in nucleoli, promoting cell proliferation by rDNA transcription, whereas it is strongly limited by its inhibitor (RNH1) throughout the rest of the cell. In stre...

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Bibliographic Details
Main Authors: Rosanna Culurciello, Ilaria Di Nardo, Andrea Bosso, Francesca Tortora, Romualdo Troisi, Filomena Sica, Angela Arciello, Eugenio Notomista, Elio Pizzo
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024005875