Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress

Engrailed Homeoprotein Protects Mesencephalic Dopaminergic Neurons from Oxidative Stress

Engrailed homeoproteins are expressed in adult dopaminergic neurons of the substantia nigra. In Engrailed1 heterozygous mice, these neurons start dying at 6 weeks, are more sensitive to oxidative stress, and progressively develop traits similar to those observed following an acute and strong oxidati...

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Bibliographic Details
Main Authors: Hocine Rekaik, François-Xavier Blaudin de Thé, Julia Fuchs, Olivia Massiani-Beaudoin, Alain Prochiantz, Rajiv L. Joshi
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715009894

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http://www.sciencedirect.com/science/article/pii/S2211124715009894

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