AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease

AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease

Abstract Microglia-driven neuroinflammation plays an important role in the development of Alzheimer’s disease. Microglia activation is accompanied by the formation and chronic expression of TLR4 inflammarafts, defined as enlarged and cholesterol-rich lipid rafts serving as an assembly platform for T...

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Bibliographic Details
Main Authors: Yi Sak Kim, Soo-Ho Choi, Keun-Young Kim, Juliana M. Navia-Pelaez, Guy A. Perkins, Seunghwan Choi, Jungsu Kim, Nicolaus Nazarenkov, Robert A. Rissman, Won-Kyu Ju, Mark H. Ellisman, Yury I. Miller
Format: Article
Language:English
Published: BMC 2024-09-01
Series:Journal of Neuroinflammation
Subjects:
AIBP
TLR4
Inflammaraft
Lipid rafts
Alzheimer’s disease
Microglia
Online Access:https://doi.org/10.1186/s12974-024-03214-4

Internet

https://doi.org/10.1186/s12974-024-03214-4

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