Dendrimers as Non-Viral Vectors in Gene-Directed Enzyme Prodrug Therapy

Dendrimers as Non-Viral Vectors in Gene-Directed Enzyme Prodrug Therapy

Gene-directed enzyme prodrug therapy (GDEPT) has been intensively studied as a promising new strategy of prodrug delivery, with its main advantages being represented by an enhanced efficacy and a reduced off-target toxicity of the active drug. In recent years, numerous therapeutic systems based on G...

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Bibliographic Details
Main Authors: Adriana Aurelia Chis, Carmen Maximiliana Dobrea, Luca-Liviu Rus, Adina Frum, Claudiu Morgovan, Anca Butuca, Maria Totan, Anca Maria Juncan, Felicia Gabriela Gligor, Anca Maria Arseniu
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
GDEPT
GDEP therapy
non-viral vector
dendrimer
delivery vehicles
gene delivery system
Online Access:https://www.mdpi.com/1420-3049/26/19/5976

Internet

https://www.mdpi.com/1420-3049/26/19/5976

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