Impact of Regulated Secretion on Antiparasitic CD8 T Cell Responses

Impact of Regulated Secretion on Antiparasitic CD8 T Cell Responses

CD8 T cells play a key role in defense against the intracellular parasite Toxoplasma, but why certain CD8 responses are more potent than others is not well understood. Here, we describe a parasite antigen, ROP5, that elicits a CD8 T cell response in genetically susceptible mice. ROP5 is secreted via...

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Bibliographic Details
Main Authors: Harshita Satija Grover, H. Hamlet Chu, Felice D. Kelly, Soo Jung Yang, Michael L. Reese, Nicolas Blanchard, Federico Gonzalez, Shiao Wei Chan, John C. Boothroyd, Nilabh Shastri, Ellen A. Robey
Format: Article
Language:English
Published: Elsevier 2014-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714003337

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http://www.sciencedirect.com/science/article/pii/S2211124714003337

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