Silybin A enhances circadian clock by targeting CRY1 and disrupting its interaction with CLOCK

Circadian clock governs a large array of physiological and metabolic functions. The amplitude decline of circadian rhythm is associated with various chronic diseases. However, few clock enhancing-molecules are known. CRY1 is one of the main components of the core circadian clock and its binding with...

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Bibliographic Details
Main Authors: Weijie Bian, Weilin Zhang, Hao Liang, Xiaowen Xie, Luhua Lai
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667142522001191