Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2
Senescent cells have long been associated with deleterious effects in aging-related pathologies, although recent studies have uncovered their beneficial roles in certain contexts, such as wound healing. We have found that hepatic stellate cells (HSCs) underwent senescence within 2 days after 2/3 par...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2022-07-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.158207 |