The difference in the cellular uptake of tocopherol and tocotrienol is influenced by their affinities to albumin

Abstract Vitamin E is classified into tocopherol (Toc) and tocotrienol (T3) based on its side chains. T3 generally has higher cellular uptake than Toc, though the responsible mechanism remains unclear. To elucidate this mechanism, we hypothesized and investigated whether serum albumin is a factor th...

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Bibliographic Details
Main Authors: Takashi Nakatomi, Mayuko Itaya-Takahashi, Yosuke Horikoshi, Naoki Shimizu, Isabella Supardi Parida, Mirinthorn Jutanom, Takahiro Eitsuka, Yoshikazu Tanaka, Jean-Marc Zingg, Tatsuya Matsura, Kiyotaka Nakagawa
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-34584-z