Lectin-Glycan Interaction Network-Based Identification of Host Receptors of Microbial Pathogenic Adhesins

ABSTRACT The first step in the infection of humans by microbial pathogens is their adherence to host tissue cells, which is frequently based on the binding of carbohydrate-binding proteins (lectin-like adhesins) to human cell receptors that expose glycans. In only a few cases have the human receptor...

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Bibliographic Details
Main Authors: Francesco S. Ielasi, Mitchel Alioscha-Perez, Dagmara Donohue, Sandra Claes, Hichem Sahli, Dominique Schols, Ronnie G. Willaert
Format: Article
Language:English
Published: American Society for Microbiology 2016-09-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00584-16