The Establishment of a Tobramycin-Responsive Whole-Cell Micro-Biosensor Based on an Artificial Ribozyme Switch

The Establishment of a Tobramycin-Responsive Whole-Cell Micro-Biosensor Based on an Artificial Ribozyme Switch

In this study, a tobramycin concentration-dependent whole-cell micro-biosensor (tob-HHAz) was constructed by fusing a tobramycin aptamer with a hammerhead ribozyme (HHR) from <i>Schistosoma mansoni</i>. The biosensor was obtained by integrating all the modules into one complete RNA seque...

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Bibliographic Details
Main Authors: Zhenzhen Wang, Jiawen Cheng, Guimin Dai, Xiaoqi Sun, Xueli Yin, Yuanyuan Zhang
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Life
Subjects:
tobramycin
tobramycin-dependent hammerhead ribozyme-based aptazyme (tob-HHAz)
whole-cell microbial sensor
Online Access:https://www.mdpi.com/2075-1729/13/7/1553

Internet

https://www.mdpi.com/2075-1729/13/7/1553

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