Mediator MED23 regulates inflammatory responses and liver fibrosis.

Liver fibrosis, often associated with cirrhosis and hepatocellular carcinomas, is characterized by hepatic damage, an inflammatory response, and hepatic stellate cell (HSC) activation, although the underlying mechanisms are largely unknown. Here, we show that the transcriptional Mediator complex sub...

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Bibliographic Details
Main Authors: Zhichao Wang, Dan Cao, Chonghui Li, Lihua Min, Gang Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000563