Age-related endolysosome dysfunction in the rat urothelium.

Lysosomal dysfunction is associated with a number of age-related pathologies that affect all organ systems. While much research has focused on neurodegenerative diseases and aging-induced changes in neurons, much less is known about the impact that aging has on lower urinary tract function. Our stud...

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Bibliographic Details
Main Authors: Steven T Truschel, Dennis R Clayton, Jonathan M Beckel, Jonathan G Yabes, Yi Yao, Amanda Wolf-Johnston, Lori A Birder, Gerard Apodaca
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5993304?pdf=render