The Role of RNA Methyltransferase METTL3 in Normal and Malignant Hematopoiesis

m6A modification is the most common modification in eukaryotes. METTL3, as a core methyltransferase of m6A modification, plays a vital role in normal and malignant hematopoiesis. Recent studies have shown that METTL3 is required for normal and symmetric differentiation of hematopoietic stem/progenit...

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Bibliographic Details
Main Authors: Xia Wu, Wu Ye, Yuping Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.873903/full