Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis

Stress signaling in breast cancer cells induces matrix components that promote chemoresistant metastasis

Abstract Metastatic progression remains a major burden for cancer patients and is associated with eventual resistance to prevailing therapies such as chemotherapy. Here, we reveal how chemotherapy induces an extracellular matrix (ECM), wound healing, and stem cell network in cancer cells via the c‐J...

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Bibliographic Details
Main Authors: Jacob Insua‐Rodríguez, Maren Pein, Tsunaki Hongu, Jasmin Meier, Arnaud Descot, Camille M Lowy, Etienne De Braekeleer, Hans‐Peter Sinn, Saskia Spaich, Marc Sütterlin, Andreas Schneeweiss, Thordur Oskarsson
Format: Article
Language:English
Published: Springer Nature 2018-09-01
Series:EMBO Molecular Medicine
Subjects:
breast cancer metastasis
chemotherapy resistance
extracellular matrix
stem cell niche
stress
Online Access:https://doi.org/10.15252/emmm.201809003

Internet

https://doi.org/10.15252/emmm.201809003

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