Genome-wide association studies of severe P. falciparum malaria susceptibility: progress, pitfalls and prospects

Genome-wide association studies of severe P. falciparum malaria susceptibility: progress, pitfalls and prospects

Abstract Background P. falciparum malaria has been recognized as one of the prominent evolutionary selective forces of human genome that led to the emergence of multiple host protective alleles. A comprehensive understanding of the genetic bases of severe malaria susceptibility and resistance can po...

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Bibliographic Details
Main Authors: Delesa Damena, Awany Denis, Lemu Golassa, Emile R. Chimusa
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Medical Genomics
Subjects:
Genome-wide association study
P. falciparum malaria
Susceptibility
Resistance
Heritability
Pathways
Online Access:http://link.springer.com/article/10.1186/s12920-019-0564-x

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http://link.springer.com/article/10.1186/s12920-019-0564-x

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