The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus.

The impact of vitamin D on dendritic cell function in patients with systemic lupus erythematosus.

Excessive activity of dendritic cells (DCs) is postulated as a central disease mechanism in Systemic Lupus Erythematosus (SLE). Vitamin D is known to reduce responsiveness of healthy donor DCs to the stimulatory effects of Type I IFN. As vitamin D deficiency is reportedly common in SLE, we hypothesi...

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Bibliographic Details
Main Authors: Ilan Ben-Zvi, Cynthia Aranow, Meggan Mackay, Anfisa Stanevsky, Diane L Kamen, L Manuela Marinescu, Christopher E Collins, Gary S Gilkeson, Betty Diamond, John A Hardin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2821911?pdf=render

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http://europepmc.org/articles/PMC2821911?pdf=render

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