Scutellaria baicalensis enhances 5-fluorouracil-based chemotherapy via inhibition of proliferative signaling pathways

Scutellaria baicalensis enhances 5-fluorouracil-based chemotherapy via inhibition of proliferative signaling pathways

Abstract Fluoropyridine-based chemotherapy remains the most widely used treatment for colorectal cancer (CRC). In this study, we investigated the mechanism by which the natural product Scutellaria baicalensis (Huang Qin; HQ) and one of its main components baicalin enhanced 5-fluorouracil (5-FU) anti...

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Bibliographic Details
Main Authors: Haizhou Liu, Hui Liu, Zhiyi Zhou, Jessica Chung, Guojing Zhang, Jin Chang, Robert A. Parise, Edward Chu, John C. Schmitz
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell Communication and Signaling
Subjects:
Scutellaria baicalensis
Colorectal cancer
5-fluorouracil
CDK-RB pathway
Baicalin
Online Access:https://doi.org/10.1186/s12964-023-01156-7

Internet

https://doi.org/10.1186/s12964-023-01156-7

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