Alteration of mRNA 5-Methylcytosine Modification in Neurons After OGD/R and Potential Roles in Cell Stress Response and Apoptosis

Alteration of mRNA 5-Methylcytosine Modification in Neurons After OGD/R and Potential Roles in Cell Stress Response and Apoptosis

Epigenetic modifications play an important role in central nervous system disorders. As a widespread posttranscriptional RNA modification, the role of the m5C modification in cerebral ischemia-reperfusion injury (IRI) remains poorly defined. Here, we successfully constructed a neuronal oxygen-glucos...

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Bibliographic Details
Main Authors: Huan Jian, Chi Zhang, ZhangYang Qi, Xueying Li, Yongfu Lou, Yi Kang, Weimin Deng, Yigang Lv, Chaoyu Wang, Wei Wang, Shenghui Shang, Mengfan Hou, Hengxing Zhou, Shiqing Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Genetics
Subjects:
m5C methylation
epitranscriptome
ischemia-reperfusion injury
oxygen-glucose deprivation/reoxygenation
cell stress
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.633681/full

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https://www.frontiersin.org/articles/10.3389/fgene.2021.633681/full

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