Essential role of neuron-enriched diacylglycerol kinase (DGK), DGKbeta in neurite spine formation, contributing to cognitive function.
BACKGROUND: Diacylglycerol (DG) kinase (DGK) phosphorylates DG to produce phosphatidic acid (PA). Of the 10 subtypes of mammalian DGKs, DGKbeta is a membrane-localized subtype and abundantly expressed in the cerebral cortex, hippocampus, and caudate-putamen. However, its physiological roles in neuro...
Hlavní autoři: | , , , , , , , , , , , |
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Médium: | Článek |
Jazyk: | English |
Vydáno: |
Public Library of Science (PLoS)
2010-01-01
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Edice: | PLoS ONE |
On-line přístup: | http://europepmc.org/articles/PMC2904696?pdf=render |