The Soluble Factor from Oral Cancer Cell Lines Inhibits Interferon-γ Production by OK-432 via the CD40/CD40 Ligand Pathway

The Soluble Factor from Oral Cancer Cell Lines Inhibits Interferon-γ Production by OK-432 via the CD40/CD40 Ligand Pathway

(1) Background: OK-432 is a penicillin-killed, lyophilized formulation of a low-toxicity strain (Su) of <i>Streptococcus pyogenes</i> (Group A). It is a potent immunotherapy agent for several types of cancer, including oral cancer. We previously showed that (i) OK-432 treatment induces a...

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Bibliographic Details
Main Authors: Go Ohe, Yasusei Kudo, Kumiko Kamada, Yasuhiro Mouri, Natsumi Takamaru, Keiko Kudoh, Naito Kurio, Youji Miyamoto
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
OK-432
conditioned medium
interferon-γ
oral cancer
CD40
Online Access:https://www.mdpi.com/2072-6694/13/13/3301

Internet

https://www.mdpi.com/2072-6694/13/13/3301

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