Left atrial remodeling in mitral regurgitation: A combined experimental-computational study.

<h4>Aims</h4>Progressive changes to left atrial (LA) structure and function following mitral regurgitation (MR) remain incompletely understood. This study aimed to demonstrate potential underlying mechanisms using experimental canine models and computer simulations.<h4>Methods</...

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Bibliographic Details
Main Authors: Sjoerd Bouwmeester, Tim van Loon, Meike Ploeg, Thomas P Mast, Nienke J Verzaal, Lars B van Middendorp, Marc Strik, Frans A van Nieuwenhoven, Lukas R Dekker, Frits W Prinzen, Joost Lumens, Patrick Houthuizen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0271588