The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11

The molecular basis of the neutralization breadth of the RBD-specific antibody CoV11

SARS-CoV-2, the virus behind the COVID-19 pandemic, has changed over time to the extent that the current virus is substantially different from what originally led to the pandemic in 2019–2020. Viral variants have modified the severity and transmissibility of the disease and continue do so. How much...

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Bibliographic Details
Main Authors: William D. Tolbert, Yaozong Chen, Lulu Sun, Mehdi Benlarbi, Shilei Ding, Rohini Manickam, Emily Pangaro, Dung N. Nguyen, Suneetha Gottumukkala, Marceline Côté, Frank J. Gonzalez, Andrés Finzi, Zahra R. Tehrani, Mohammad M. Sajadi, Marzena Pazgier
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
neutralizing antibody
VH 3-53 germline gene (IGHV3-53*01)
receptor binding domain (RBD)
variants of concern (VOC)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178355/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1178355/full

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