Circulating LOXL2 Levels Reflect Severity of Intestinal Fibrosis and GALT CD4+ T Lymphocyte Depletion in Treated HIV Infection

Circulating LOXL2 Levels Reflect Severity of Intestinal Fibrosis and GALT CD4+ T Lymphocyte Depletion in Treated HIV Infection

Background: Incomplete immune reconstitution may occur despite successful antiretroviral therapy (ART). Gut-associated lymphoid tissue (GALT) fibrosis may contribute via local CD4+ T lymphocyte depletion, intestinal barrier disruption, microbial translocation, and immune activation. Methods: In a c...

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Bibliographic Details
Main Authors: Sophie Seang, Anoma Somasunderam, Maitreyee Nigalye, Ma Somsouk, Timoty W. Schacker, Joyce L. Sanchez, Peter W. Hunt, Netanya S. Utay, Jordan E. Lake
Format: Article
Language:English
Published: Case Western Reserve University 2017-06-01
Series:Pathogens and Immunity
Subjects:
GALT, HIV, fibrosis, immune reconstitution
Online Access:https://paijournal.com/index.php/paijournal/article/view/180

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https://paijournal.com/index.php/paijournal/article/view/180

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