Critical pharmacokinetic and pharmacodynamic drug-herb interactions in rats between warfarin and pomegranate peel or guava leaves extracts

Critical pharmacokinetic and pharmacodynamic drug-herb interactions in rats between warfarin and pomegranate peel or guava leaves extracts

Abstract Background In-depth information of potential drug-herb interactions between warfarin and herbal compounds with suspected anticoagulant blood thinning effects is needed to raise caution of concomitant administration. The current study aimed to investigate the impact of co-administration of p...

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Bibliographic Details
Main Authors: Maisa Alnaqeeb, Kenza A. Mansor, Eyad M. Mallah, Bayan Y. Ghanim, Nasir Idkaidek, Nidal A. Qinna
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Drug-herb interactions
Bleeding
Pomegranate peel
Ellagic acid
Guava leaves
Cytochrome P450
Online Access:http://link.springer.com/article/10.1186/s12906-019-2436-5

Internet

http://link.springer.com/article/10.1186/s12906-019-2436-5

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