Metabolite itaconate in host immunoregulation and defense

Abstract Metabolic states greatly influence functioning and differentiation of immune cells. Regulating the metabolism of immune cells can effectively modulate the host immune response. Itaconate, an intermediate metabolite derived from the tricarboxylic acid (TCA) cycle of immune cells, is produced...

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Bibliographic Details
Main Authors: Wenchang Yang, Yaxin Wang, Kaixiong Tao, Ruidong Li
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-023-00503-3