The presence of Merkel cell carcinoma polyomavirus is associated with a distinct phenotype in neoplastic Merkel cell carcinoma cells and their tissue microenvironment.

The presence of Merkel cell carcinoma polyomavirus is associated with a distinct phenotype in neoplastic Merkel cell carcinoma cells and their tissue microenvironment.

<h4>Aims</h4>Merkel cell carcinoma (MCC) is an aggressive primary neuroendocrine tumor of the skin, associated with Merkel cell polyomavirus (MCPyV) in 49-89% of cases, depending on the country of origin and the techniques of detection. The presence of MCPyV defines heterogeneity in MCC;...

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Main Authors: María-Dolores Mendoza, Carlos Santonja, Carmen Gonzalez-Vela, Angel Concha, Nicolás Iglesias Pena, Eva-Maria Andrés-Esteban, Jose Pedro Vaque, Laura Cereceda, Raquel Pajares, H Kutzner, Luis Requena, Miguel A Piris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0232517

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https://doi.org/10.1371/journal.pone.0232517

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