Monocyte/Macrophage‐Mediated Transport of Dual‐Drug ZIF Nanoplatforms Synergized with Programmed Cell Death Protein‐1 Inhibitor Against Microsatellite‐Stable Colorectal Cancer

Monocyte/Macrophage‐Mediated Transport of Dual‐Drug ZIF Nanoplatforms Synergized with Programmed Cell Death Protein‐1 Inhibitor Against Microsatellite‐Stable Colorectal Cancer

Abstract Microsatellite‐stable colorectal cancer (MSS‐CRC) exhibits resistance to programmed cell death protein‐1 (PD‐1) therapy. Improving the infiltration and tumor recognition of cytotoxic T‐lymphocytes (CTLs) is a promising strategy, but it encounters huge challenges from drug delivery and mecha...

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Bibliographic Details
Main Authors: Xietao Ye, Yuping Liu, Liangyin Wei, Yeyang Sun, Xiaoran Zhang, Hong Wang, Hong Guo, Xiaoying Qin, Xiaoqi Li, Ding Qu, Jiege Huo, Yan Chen
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Advanced Science
Subjects:
antigen transport
combination therapy
MHC‐I
monocyte/macrophage transport
PD‐1 inhibitors
Online Access:https://doi.org/10.1002/advs.202405886

Internet

https://doi.org/10.1002/advs.202405886

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