Ube4A maintains metabolic homeostasis and facilitates insulin signaling in vivo

Ube4A maintains metabolic homeostasis and facilitates insulin signaling in vivo

Objective: Defining the regulators of cell metabolism and signaling is essential to design new therapeutic strategies in obesity and NAFLD/NASH. E3 ubiquitin ligases control diverse cellular functions by ubiquitination-mediated regulation of protein targets, and thus their functional aberration is a...

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Bibliographic Details
Main Authors: Sandip Mukherjee, Molee Chakraborty, Eliwaza N. Msengi, Jake Haubner, Jinsong Zhang, Matthew J. Jellinek, Haley L. Carlson, Kelly Pyles, Barbara Ulmasov, Andrew J. Lutkewitte, Danielle Carpenter, Kyle S. McCommis, David A. Ford, Brian N. Finck, Brent A. Neuschwander-Tetri, Anutosh Chakraborty
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Molecular Metabolism
Subjects:
Ube4A
Ubiquitination
Obesity
NAFLD
Insulin/Akt signaling
APPL1
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877823001011

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http://www.sciencedirect.com/science/article/pii/S2212877823001011

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