Reversion of antibiotic resistance in multidrug-resistant pathogens using non-antibiotic pharmaceutical benzydamine

Liu et al. describe the antibiotic adjuvant effect of the FDA approved drug, benzydamine, for the treatment of infections caused by multidrug-resistant bacteria. Mechanistically, benzydamine dissipates membrane potential in both Gram-positive and Gram-negative bacteria, upregulates the transmembrane...

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Bibliographic Details
Main Authors: Yuan Liu, Ziwen Tong, Jingru Shi, Yuqian Jia, Tian Deng, Zhiqiang Wang
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02854-z