Reversion of antibiotic resistance in multidrug-resistant pathogens using non-antibiotic pharmaceutical benzydamine
Liu et al. describe the antibiotic adjuvant effect of the FDA approved drug, benzydamine, for the treatment of infections caused by multidrug-resistant bacteria. Mechanistically, benzydamine dissipates membrane potential in both Gram-positive and Gram-negative bacteria, upregulates the transmembrane...
Main Authors: | Yuan Liu, Ziwen Tong, Jingru Shi, Yuqian Jia, Tian Deng, Zhiqiang Wang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-11-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02854-z |
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