In vitro oogenesis from murine premeiotic germ cells using a new three-dimensional culture system

Abstract A faithful reconstitution of the complete process of oogenesis in vitro is helpful for understanding the molecular mechanisms, genetics, and epigenetic changes related to gametogenesis; it can also be useful for clinical drug screening, disease research, and regenerative medicine. To this e...

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Bibliographic Details
Main Authors: Lu Wang, Zi-Hui Yan, Tao-Ran He, Hai-Xia Liu, Yu-Kang Li, Yi-Lin Niu, Jun-Jie Wang, Massimo De Felici, Wei Ge, Wei Shen
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01577-w