A druggable secretory protein maturase of Toxoplasma essential for invasion and egress

A druggable secretory protein maturase of Toxoplasma essential for invasion and egress

Micronemes and rhoptries are specialized secretory organelles that deploy their contents at the apical tip of apicomplexan parasites in a regulated manner. The secretory proteins participate in motility, invasion, and egress and are subjected to proteolytic maturation prior to organellar storage and...

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Bibliographic Details
Main Authors: Sunil Kumar Dogga, Budhaditya Mukherjee, Damien Jacot, Tobias Kockmann, Luca Molino, Pierre-Mehdi Hammoudi, Ruben C Hartkoorn, Adrian B Hehl, Dominique Soldati-Favre
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
Apicomplexa
Toxoplasma gondii
aspartyl protease
peptidomimetic inhibitor
micronemes and rhoptries
invasion and egress
Online Access:https://elifesciences.org/articles/27480

Internet

https://elifesciences.org/articles/27480

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