Inulin-Type Fructans Modulates Pancreatic–Gut Innate Immune Responses and Gut Barrier Integrity during Experimental Acute Pancreatitis in a Chain Length-Dependent Manner

Inulin-Type Fructans Modulates Pancreatic–Gut Innate Immune Responses and Gut Barrier Integrity during Experimental Acute Pancreatitis in a Chain Length-Dependent Manner

Acute pancreatitis (AP) is a common abdominal inflammatory disorder and one of the leading causes of hospital admission for gastrointestinal disorders. No specific pharmacological or nutritional therapy is available but highly needed. Inulin-type fructans (ITFs) are capable of modifying gut immune a...

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Bibliographic Details
Main Authors: Yue He, Chengfei Wu, Jiahong Li, Hongli Li, Zhenghua Sun, Hao Zhang, Paul de Vos, Li-Long Pan, Jia Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Immunology
Subjects:
dietary fibers
inflammation
pancreatic–intestinal immunity
signaling kinases
tight junction proteins
antimicrobial peptides
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01209/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.01209/full

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