The Activin Receptor, Activin-Like Kinase 4, Mediates Toxoplasma Gondii Activation of Hypoxia Inducible Factor-1

To grow and cause disease, intracellular pathogens modulate host cell processes. Identifying these processes as well as the mechanisms used by the pathogens to manipulate them is important for the development of more effective therapeutics. As an example, the intracellular parasite Toxoplasma gondii...

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Bibliographic Details
Main Authors: Agnieszka Lis, Mandi Wiley, Joan Vaughan, Peter C. Gray, Ira J. Blader
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2019.00036/full