A model for sigma factor competition in bacterial cells.

Sigma factors control global switches of the genetic expression program in bacteria. Different sigma factors compete for binding to a limited pool of RNA polymerase (RNAP) core enzymes, providing a mechanism for cross-talk between genes or gene classes via the sharing of expression machinery. To ana...

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Bibliographic Details
Main Authors: Marco Mauri, Stefan Klumpp
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4191881?pdf=render