Large Cell Neuro-Endocrine Carcinoma of the Lung: Current Treatment Options and Potential Future Opportunities

Large Cell Neuro-Endocrine Carcinoma of the Lung: Current Treatment Options and Potential Future Opportunities

Large-cell neuroendocrine carcinomas of the lung (LCNECs) are rare tumors representing 1–3% of all primary lung cancers. Patients with LCNEC are predominantly male, older, and heavy smokers. Histologically, these tumors are characterized by large cells with abundant cytoplasm, high mitotic rate, and...

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Bibliographic Details
Main Authors: Miriam Grazia Ferrara, Alessio Stefani, Michele Simbolo, Sara Pilotto, Maurizio Martini, Filippo Lococo, Emanuele Vita, Marco Chiappetta, Alessandra Cancellieri, Ettore D’Argento, Rocco Trisolini, Guido Rindi, Aldo Scarpa, Stefano Margaritora, Michele Milella, Giampaolo Tortora, Emilio Bria
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
large cell
lung cancer
review
neuro-endocrine
treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.650293/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.650293/full

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