Anti-Inflammatory Effects of Idebenone Attenuate LPS-Induced Systemic Inflammatory Diseases by Suppressing NF-κB Activation

Anti-Inflammatory Effects of Idebenone Attenuate LPS-Induced Systemic Inflammatory Diseases by Suppressing NF-κB Activation

Inflammation is a natural protective process through which the immune system responds to injury, infection, or irritation. However, hyperinflammation or long-term inflammatory responses can cause various inflammatory diseases. Although idebenone was initially developed for the treatment of cognitive...

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Bibliographic Details
Main Authors: Yumin Choi, Young-Lai Cho, Sujeong Park, Minkyung Park, Keun-Seok Hong, Young Jun Park, In-Ah Lee, Su Wol Chung, Heedoo Lee, Seon-Jin Lee
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Antioxidants
Subjects:
anti-inflammation
inflammatory disease model
NF-κB
ROS
idebenone
Online Access:https://www.mdpi.com/2076-3921/13/2/151

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https://www.mdpi.com/2076-3921/13/2/151

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