Detecting Rewiring Events in Protein-Protein Interaction Networks Based on Transcriptomic Data

Proteins rarely carry out their cellular functions in isolation. Instead, eukaryotic proteins engage in about six interactions with other proteins on average. The aggregated protein interactome of an organism forms a “hairy ball”-type protein-protein interaction (PPI) network. Yet, in a typical huma...

Full description

Bibliographic Details
Main Authors: Markus Hollander, Trang Do, Thorsten Will, Volkhard Helms
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Bioinformatics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2021.724297/full