IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients

IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients

BackgroundIn the U.S., African Americans (AAs) present with the highest incidence and mortality rates for Colorectal Cancer (CRC). When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previo...

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Bibliografski detalji
Glavni autori: Marzia Spagnardi, Jenny Paredes, Jovanny Zabaleta, Jone Garai, Tiana Reyes, Laura A. Martello, Jennie L. Williams
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2022-12-01
Serija:Frontiers in Oncology
Teme:
African American
colon cancer
health disparities
Interleukin-1β
5-FU
IL-1Ra
Online pristup:https://www.frontiersin.org/articles/10.3389/fonc.2022.1010380/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.1010380/full

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