Downregulation of SIRT2 Inhibits Invasion of Hepatocellular Carcinoma by Inhibiting Energy Metabolism

Hepatocellular carcinoma (HCC) is one of the most common neoplasms, and metastasis is the most important feature for HCC-related deaths. Mounting evidence implies the dynamic regulatory role of SIRT2, a histone deacetylase, in cancer cells. Unfortunately, the role of SIRT2 and the antitumor activity...

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Bibliographic Details
Main Authors: Shan Huang, Zhenguo Zhao, Dehua Tang, Qian Zhou, Yang Li, Lixing Zhou, Yuyao Yin, Yuming Wang, Yida Pan, Robert Gregory Dorfman, Tingsheng Ling, Mingming Zhang
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523317302449