Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor

Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor

Summary: Cells of origin in cancer determine tumor phenotypes, but whether lineage-defining transcription factors might influence tissue specificity of tumorigenesis among organs with similar developmental traits are unknown. We demonstrate here that tumor development and progression markedly differ...

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Bibliographic Details
Main Authors: Elin Schoultz, Shawn Liang, Therese Carlsson, Stefan Filges, Anders Ståhlberg, Henrik Fagman, Clotilde Wiel, Volkan Sayin, Mikael Nilsson
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Genetics
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223011483

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http://www.sciencedirect.com/science/article/pii/S2589004223011483

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