Genome Editing Using Mammalian Haploid Cells
Haploid cells are useful for studying gene functions because disruption of a single allele can cause loss-of-function phenotypes. Recent success in generating haploid embryonic stem cells (ESCs) in mice, rats, and monkeys provides a new platform for simple genetic manipulation of the mammalian genom...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-10-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1422-0067/16/10/23604 |