Integrin β3 Induction Promotes Tubular Cell Senescence and Kidney Fibrosis

Tubular cell senescence is a common biologic process and contributes to the progression of chronic kidney disease (CKD); however, the molecular mechanisms regulating tubular cell senescence are poorly understood. Here, we report that integrin β3 (ITGB3) expression was increased in tubular cells and...

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Bibliographic Details
Main Authors: Shen Li, Song Jiang, Qingyan Zhang, Bo Jin, Daoyuan Lv, Wenju Li, Min Zhao, Chunming Jiang, Chunsun Dai, Zhihong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.733831/full