Comparative Analysis of the Secretome and Interactome of Trypanosoma cruzi and Trypanosoma rangeli Reveals Species Specific Immune Response Modulating Proteins

Chagas disease, a zoonosis caused by the flagellate protozoan Trypanosoma cruzi, is a chronic and systemic parasitic infection that affects ~5–7 million people worldwide, mainly in Latin America. Chagas disease is an emerging public health problem due to the lack of vaccines and effective treatments...

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Main Authors: Renata Watanabe Costa, Marina Ferreira Batista, Isabela Meneghelli, Ramon Oliveira Vidal, Carlos Alcides Nájera, Ana Clara Mendes, Izabela Augusta Andrade-Lima, José Franco da Silveira, Luciano Rodrigo Lopes, Ludmila Rodrigues Pinto Ferreira, Fernando Antoneli, Diana Bahia
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01774/full