Comprehensive and systemic optimization for improving the yield of SARS-CoV-2 spike pseudotyped virus

Virus neutralization assay is principally conducted by measuring the ability of the antibodies in patient sera to prevent the infection of susceptible cells by the virus. As SARS-CoV-2 is classified as a risk group 3 pathogen, neutralization assay using a live virus needs to be handled in a biosafet...

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Bibliographic Details
Main Authors: Xinping Fu, Lihua Tao, Xiaoliu Zhang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120302552