Calcification and Oxidative Modifications Are Associated With Progressive Bioprosthetic Heart Valve Dysfunction

BackgroundBioprosthetic heart valves (BHVs), fabricated from glutaraldehyde‐pretreated bovine pericardium or porcine aortic valves, are widely used for the surgical or interventional treatment of heart valve disease. Reoperation becomes increasingly necessary over time because of BHV dysfunction. Me...

Full description

Bibliographic Details
Main Authors: Suengwon Lee, Robert J. Levy, Abigail J. Christian, Stanley L. Hazen, Nathan E. Frick, Eric K. Lai, Juan B. Grau, Joseph E. Bavaria, Giovanni Ferrari
Format: Article
Language:English
Published: Wiley 2017-05-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.117.005648